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Gamers Help Solve HIV Enzyme Structure

by Jake Weston, posted on 20 September 2011 / 1,974 Views

Games have long been the source of scientific study, but rarely has it been the other way around. Recently, however, a recent study published by the journal Nature Structural & Molecular Biology has revealed that gamers helped scientists determine the structure of of a monomeric protease enzyme, an essential component of various retroviruses, including HIV. 

Scientists gathered a group of gamers to compete with each other in Foldit, a game designed by researchers at the University of Washington. The game gives players various tools to unfold virtual models of amino acid chains, which is essential to understanding their structure, as well as the structure of the proteins they construct.

Evidently, the enzyme structure, which scientists have been trying to determine for decades, was determined by gamers after three weeks of playing the game. Where were the game players able to succeed where scientists have failed? According to one researcher Firas Khatib, it was the power of intuition.

"People have spatial reasoning skills, something computers are not yet good at," said Khatib, "The ingenuity of game players is a formidable force that, if properly directed, can be used to solve a wide range of scientific problems." 

Hopefully this study will greatly aid researchers in the fight against AIDS and HIV, and here's also hoping that future studies use similar methods to use gaming as a positive force.


9 Comments

usrevenge (on 20 September 2011)

inb4 fox news claims this is the source of all crime in the USA.


lololol (on 20 September 2011)

More like inb4 Fox News twists the story so that it reads "Gamers help HIV... and terrorism"


  • +2
Jexy (on 20 September 2011)

Solving an AIDS problem for gamers isn't nearly as hard as beating Silver Surfer


demonfox13 (on 20 September 2011)

ROFL now that you mention it that was a game I wanted to kill myself playing. I would much rather re-beat Battletoads today than even begin playing Silver Surfer. In my lifetime I only met a single person who actually beat that game. An older cousin of mine (he's currently a firefighter) named Hugo. Ever since then he remained a legend to me lol.


  • 0
DonFerrari (on 20 September 2011)

Good were the times were most people couldn't finish some games, nowadays if a game isn't easily beaten up everybody shout "broken" and the game sink


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Rath (on 20 September 2011)

Now when people ask you what you do, instead of saying 'I sit around all day playing computer games' you can say 'I'm working on HIV research'


sweatface7 (on 20 September 2011)

crazy, now i bet they look at gamers in a different way than just some nerds who play games!


padib (on 20 September 2011)

Mind-boggling, what a pleasure to see gamers put to constructive use.


Tammi (on 20 September 2011)

Cool. Maybe the scientists should be paid ONLY when they actually figure something out. If gamers can do this, they should have been able to as well.


UnknownFact (on 20 September 2011)

This article says nothing.


Rafux (on 20 September 2011)

Very interesting


UltimateUnknown (on 20 September 2011)

I would have liked to give the game a try, I did always love the biology behind the structure of living organisms.