Mercenary Mode
Successfully complete the game once on any either difficulty setting and wait for the credits to end, then save the "Next Game" file to unlock "The Mercenaries" mini-game. Start a new game, choose that saved game, then select "The Mercenaries" mode. This mode involves controlling Carlos, Mikhal, or Nikoli from the train to the starting room with a two minute timer. Killing the various opponents and rescuing civilians during the journey will add extra money and more time to the clock. A rank and money will be awarded after the game is completed. The money can be used to purchase better weapons and infinite ammunition.

Boutique Key
Successfully complete the game once and wait for the credits to end, then save the "Next Game" file to receive the key to the Boutique on the first street at the start of the game. Use the key to enter and change into an alternate costume.

Jill's diary:
To get Jill's Diary (a file), collect all thirty files in the game in order. Then the first file (Instructions Manual, blue) will become Jill's Diary.

Barry Burton ending:
The only way to see Barry is if ending B is unlocked. To get this ending, jump off the bridge when fighting Nemesis Type B. After the jump off decision, the final area of the game will take a somewhat different path. You will have to fight off Nicholai in a chopper. It is recommended that you bring a Magnum and Grenade Launcher (or Rocket Launcher if it has been found). You can also choose to negotiate with him.

Barry Burton ending 2:
Jump off the bridge. Play until you reach the room with the Radar Tracker. Take it, and try to leave the room using the door you entered. Nicholai will call you. After killing him, Carlos will enter. After talking with him, leave the room (do not use the hatch to the Rail Cannon). Turn around and get in the radar device room again. Carlos and Jill will listen to a radio call from Barry and the game will continue with the final scenes.

Enhanced Weapons/Ammo:
You can only create enhanced ammo while playing under the hard difficulty setting. When creating ammo with the reloading tool, save enough gunpowder to mix up the same type of ammo eight times. On the eighth time, the game will prompt "Do you want to create the enhanced ammo?". Select "Yes". This ammo is more powerful, may have slightly different effects, and once loaded into a weapon will change it into an "enhanced weapon". You can only create two types of enhanced ammo: 9mm handgun bullets and shot gun shells. The only different effects the new bullets have is that they are far more powerful.

Alternate costumes:
Successfully complete the game under the easy difficulty setting with any rank better than F to unlock Jill's costume from the original Resident Evil and Regina's costume from Dino Crisis. To unlock three additional costumes, successfully complete the game under the hard difficulty setting with a rank of A. This will unlock police miniskirt, disco, and biker costumes.

Epilogues:
Successfully complete the game under the hard difficulty setting to unlock Epilogues. Epilogues are a short diary description of each character in the entire Resident Evil series which describes what happened with that specific person after their adventure. Getting better ratings can unlock the other epilogues. There are eight total Epilogues that can be unlocked.

Get New Weapons and Infinite Bullets in the Game
Start a game in Normal Mode.
Every time you beat Nemesis you'll get:

1 time: Eagle Parts A
2 times: Eagle Parts B
3 times: 3 Heath Sprays
4 times: Shotgun Parts A
5 times: Shotgun Parts B
6 times: 3 Health Sprays
Every time: Assault Rifle

If this is your second visit in the game(you finished the game and loaded your save)you'll get if you've beaten Nemesis everytime instead of the Assault Rifle the Infinite Bullets.Use it on one of your weapons and you'll have Infinite Ammo then.

The Worm:
You actually do not have to fight the Worm the first time you meet him, when you fall into the sewer. After he pops out of the wall the first time, just run to your right and hit the first switch (make sure the worm comes out of the wall). Then, run to the other side of the sewer and hit the second switch (this one may be difficult -- also make sure the worm comes out again). Then, press the button for the ladder and you just saved yourself some life and ammunition.

Custom shotgun:
Play the game under the hard difficulty setting. Defeat Nemesis for the fourth time and pick up the small silver box that he dropped. It will contain M37 Parts A. Defeat Nemesis a fifth time and get the M37 Parts B. Combine these two parts to get a western custom shotgun with six rounds. This gun uses the standard 12 gauge shotgun shells.

Rocket launcher:
In the dead factory, go to the machine next to the water sample puzzle. Use the facility key where that game states a small plastic card can be inserted. Take the other facility key that is given and go to the steaming room where the small card activated elevator is located .Go down and use the facility key on the door where that game states a small plastic card can be inserted. You will find a rocket launcher with four shots at this location.

Mercenary mode item box:
Once you complete mercenary mode with each character and bought all the weapons you can access the item box, but it only contains a knife.

Extra Nemesis fight in mercenary mode:
In the parking lot, there will be some zombies. If you do not kill the last two nearest to the door, when you go out in front of the bus you will have to face Nemesis as you did when you were playing as Carlos in the actual game (with all of his tentacles). If you do not stop running, you probably will not have to face him. Note: He only comes down when you go to the viewpoint in which you can see the top of the bus. Also, it is not smart to fight him because it must be done with a rocket launcher and some zombied friends.

Run on one foot:
When running, quickly and repeatedly tap Square. Jill will run on one foot, and her other foot will never touch the ground.

Spinning Jill:
Note: A controller with an auto-fire feature is required for this trick. Turn on the auto-fire, then have Jill walk backwards and press the bvutton to have her turn around. If done correctly, she will spin around on one foot.

Campaign sign:
Go to the end of the hall with the save room behind the restaurant to find political campaign signs. Look closely to will see a sign that says "OTOM for U...S Senat".

Locker combination:
When entering the Police Station and going into the door in the top left corner, you will reach a room with zombies. After killing them, enter the next room, which contains the lockers. Go to the other side to find a locker with a light on it. The game will prompt for a code. The code (varies by game) is either "0131", "0513", "4011", or "4312".

Park fountain solution:
When using the water control unit in Raccoon Park to drain the fountain, you have to align the gray and black gears. The gears need to be moved in the following order to correctly align them and drain the fountain. Move the bottom left black gear up. Move the top center gray gear down. Move the top right gray gear to the left. Move the bottom right black gear up. Move the top center gray gear down. Move the top left black gear to the right.